Hyperhidrosis is a condition characterized by excessive sweating, beyond what is physiologically necessary for thermoregulation. It is a disorder associated with the eccrine sweat glands.
Eccrine glands are located over the entire body surface. However, the density of their distribution varies, with the greatest concentration found in the axilla, palms, soles of the feet, and face. These glands are distributed throughout the skin in a common anatomic pattern and at a depth of 2-6 mm. They secrete a clear, odorless fluid consisting of ~99% water and ~1% sodium chloride and potassium..
Osmidrosis is a condition characterized by strong and unpleasant body odor. The odor occurs as bacteria residing on the skin breaks down the fluid released by the apocrine sweat glands.
Apocrine glands are located in areas of the body with a high concentration of hair follicles, such as the axilla, the perianal region, and the genital region. These glands are embedded within the dermis-hypodermis interface at a depth of 6-8 mm and secrete a thick, milky, odorless fluid rich in proteins, ammonia, lipids and carbohydrates.